Cell· Jun W. Kim, Christina M. Bebber, Yuqin Dai, Sarah Bopp, Anna Edenhofer, Albert M. Li, Thomas Rösner, Lena Berning, Ming Yang, Logan B. Leak, Jenny Stroh, Bindesh Shrestha, Ali T. Abdallah, Dimitrios Prymidis, Hernando J. Olivos, Maya Baron, Thuyen Nguyen, Yan Ting Shue, Yoko Nishiga, Alexandros P. Drainas, Andrea C. Chaikovsky, Krystina Szylo, Yang Li, Yun P. Kang, Parvathy Manoj, Alvaro Quintanal Villalonga, Charles M. Rudin, Gina M. DeNicola, Scott J. Dixon, Christian Frezza, Jiangbin Ye, Silvia von Karstedt, Julien Sage·· 18 小时前AI 评分42
细胞状态特异的代谢网络决定小细胞肺癌铁死亡与凋亡命运
Cell-state-specific metabolic networks govern ferroptosis versus apoptosis in small cell lung cancer
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小细胞肺癌（SCLC）的细胞状态决定癌细胞对代谢应激的响应方式，其代谢可塑性决定细胞走向铁死亡还是凋亡。该研究揭示细胞状态特异的代谢网络如何调控这两种死亡命运，为理解 SCLC 的代谢异质性提供了依据。
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来源：Cell · cell.com