OmniVira 知识库发布，收录 8072 条病毒溢出与跨物种传播证据
OmniVira: a knowledgebase of source-linked evidence on viral spillover and cross-species transmission
OmniVira 是一个把文献发现整理为结构化、可追溯记录的病毒溢出与跨物种传播知识库，每条 OmniVira Evidence（OVE）记录都关联到原文与支持文本。该库用领域本体把证据分为人兽共患监测、传播证据、实验感染、功能机制和基因组演化五类共 14 种证据类型，并结合本体引导的人工整理、大语言模型辅助的文献筛选与候选提取、自动一致性检查和策展人复核，实现每日更新。
来源：Nucleic Acids Research · doi.org
Zoonotic viral emergence poses persistent challenges to global health, yet evidence relevant to spillover and cross-species transmission is dispersed across surveillance, epidemiological, experimental, mechanistic, and genomic studies. Here, we present OmniVira (https://omnivira.org/), a curated knowledgebase that transforms literature-derived findings into structured, traceable, and reusable OmniVira Evidence (OVE) records. OmniVira implements an auditable article–evidence framework linking individual findings and supporting text to normalized virus, host, and geographic entities, and relevant biological context. A domain-specific ontology organizes 14 evidence types into five categories: Zoonotic Surveillance, Transmission Evidence, Experimental Infection, Functional Mechanism, and Genomic Evolution. The platform integrates ontology-guided curation, large language model-assisted literature screening and candidate extraction, automated consistency checks, and curator review of flagged or ambiguous records, enabling daily updates. As of 4 August 2026, OmniVira contained 8072 publicly retrievable OVE records derived from 2623 source articles, spanning 60 ICTV virus families, 55 host orders, and 121 countries. Its responsive interface supports evidence-centred retrieval, source-text verification, and exploration of linked virus–host–literature relationships across desktop and mobile browsers. OmniVira provides a transparent, context-preserving resource for systematic comparison and synthesis of evidence related to zoonotic viral emergence and cross-species transmission.