Cell Reports Medicine· Joanne Marie M. Del Rosario, Sneha Vishwanath, Simon D.W. Frost, Sneha B. Sujit, Sruthika K. Ashokan, Robert Vendramelli, Matteo Ferrari, George W. Carnell, Lucrezia Vianello, Matteo Pagliari, Sami Ramzi, Valentina Maria Panzarin, Elisa Mazzacan, Andrea Fortin, Marta Vascellari, Thang Truong, Paul Tonks, Ana Liza Ortiz, Chloe Qingzhou Huang, Sebastian Einhauser, Michael Schachtner, Benedikt Asbach, Daniel Matthew L. Storisteanu, Nigel J. Temperton, Matthew N. Davies, David Moss, Rebecca Kinsley, Ralf Wagner, Darwyn Kobasa, Francesco Bonfante, Jonathan L. Heeney·· 22 小时前AI 评分58
多抗原 mRNA 疫苗对全球多种 H5Nx 流感病毒显示广谱保护
Broad vaccine protection against globally diverse influenza A/H5Nx viruses
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Del Rosario 等人利用数字免疫优化合成疫苗技术，设计了一款多抗原 mRNA 疫苗，对全球不同且持续演化的 H5Nx 流感病毒产生广谱免疫原性和保护。研究提示，计算设计的多价抗原可作为应对当前及未来 H5Nx 多样性的准备工具。
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来源：Cell Reports Medicine · cell.com