Cell Reports Medicine· Vinicius A. Schoeps, Pavan Bhargava, Gina Chang, Danielle J. Caruso, Dohee Kim, Akash Virupakshaiah, Janet Chong, Gregory Aaen, Jennifer S. Graves, Leslie A. Benson, Mark P. Gorman, Mary Rensel, Aaron W. Abrams, Soe S. Mar, Timothy Lotze, Tanuja Chitnis, Amy T. Waldman, Lauren B. Krupp, Moses Rodriguez, Jan-Mendelt Tillema, John W. Rose, Teri Schreiner, T. Charles Casper, Helen Tremlett, John W. Newman, Kamil Borkowski, Emmanuelle Waubant, the US Network of Pediatric MS Centers·· 18 小时前AI 评分47
丙酸与儿童期起病多发性硬化的疾病活动度相关
Propionate, a short-chain fatty acid, is associated with disease activity in pediatric-onset multiple sclerosis
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Schoeps 等人在多发性硬化发病后不久的年轻患者中发现，血浆和粪便中较高的丙酸水平与较低的临床和影像学疾病活动度持续相关。这一肠道微生物来源的短链脂肪酸可能调节早期炎症活动，支持开展靶向补充的临床试验。
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来源：Cell Reports Medicine · cell.com