Cell Reports Medicine· David Braun, Nicholas Dana, Hilary R. Hernan, Shalini Sahni, Christina M. Scribano, Christin Johnson, Lindsey Vedder, Erika von Euw, Julie Zweng, Ellen Wargowski, Aishwarya Sunil, Deepa Sharma, Josh Routh, Katherine Rexroad, Amreen Nasreen, Payton McDonnell, Victor Jergens, Catarina Costa, Richard Zuniga, Giuseppe V. Toia, Paras M. Patel, Stephanie McGregor, Robert C.G. Martin, Umair Majeed, Debabrata Mukhopadhyay, Yanyan Lou, Nima Kokabi, James W. Jakub, David Hays, Andrew K. Godwin, Victoria Giffi, Alexander Gelbard, Andreas Friedl, Emma Kate Duimstra, Roxana S. Dronca, Ruqin Chen, Heather Chalfin, Santanu Bhattacharya, Barbara Broome, Hani M. Babiker, Tarun Chandra, Sean Caenepeel, Laura C.F. Hrycyniak, Chetan Sood, Hilario Ramos, Premal Patel, Pooja Advani, Hinco J. Gierman, Janis Taube·· 5 天前AI 评分58
用常规临床活检的活体肿瘤片段预测免疫治疗反应
Prediction of immunotherapy response using live tumor fragments from routine clinical biopsies
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Braun 等利用常规穿刺和钳取活检取得的活体肿瘤组织，在体外测量免疫治疗反应，结果与一个小型患者队列的临床结局一致，其中包括被现有生物标志物检测误判的患者。该研究提示，离体活肿瘤片段或可作为预测癌症免疫治疗获益的补充手段。
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来源：Cell Reports Medicine · cell.com