在全球南方建设常规实验室基因组学能力的十条简单规则
Ten simple rules to build genomics capacity for routine laboratory practice in the Global South
针对全球南方可持续基因组学能力建设，文章提出十条简单规则，强调不能只靠技术转移，还需以实验室人员的工作流程和现有专长为出发点，依靠机构协作与长期融入卫生系统。规则聚焦本地情境、战略规划、持续学习和公平合作，为低收入和中等收入国家实验室将基因组技术从研究工具转为诊断、监测与决策的常规手段提供路线图。
来源：PLOS Computational Biology · journals.plos.org
by Emilyn Costa Conceição, Abhinav Sharma, Davi Josué Marcon, Layana Rufino Ribeiro, Danna Karen Corrêa dos Santos, Lilian Eduarda de Oliveira Freitas, Alex Brito Souza, Hendor Neves Ribeiro de Jesus, Maria Cristina da Silva Lourenço, Valnete das Graças Dantas Andrade, Marco Aurélio Almeida de Oliveira, Tatyana Costa Amorim Ramos, Ítalo José Mesquita Cavalcante, Arabela Leal e Silva de Melo, Nabila Ismail, Tulio de Oliveira, Robin Mark Warren, Adriana Ayden Ferreira, Theolis Costa Barbosa Bessa, Cristiane Cunha Frota, Philip Noel Suffys, Karla Valéria Batista Lima, REVIGET Consortium
Developing sustainable genomics capacity in the Global South requires more than technology transfer; it depends on human-centered approaches based on the workflows and existing expertise of laboratory personnel, institutional collaboration, and long-term integration into health systems. Drawing on lessons learned from regional capacity-building initiatives, this article proposes ten simple rules for implementing and sustaining genomics capacity within public health and clinical laboratory settings. These rules emphasize local context, strategic planning, continuous learning, and equitable collaboration. Together, they provide a roadmap for laboratories aiming to transform genomic technologies from research tools for diagnosis, surveillance and decision-making, into routine instruments for public health in low- and middle-income countries.