AnnelidaDB:覆盖环节动物门分类与多组学资源的综合平台
AnnelidaDB: a comprehensive platform of taxonomic and multi-omic resources across annelids
AnnelidaDB(www.annelidadb.com)是一个以物种为中心、基于更新后的系统发育框架构建的环节动物多组学数据库,整合了基因组、线粒体基因组、转录组、蛋白组、表观基因组、单细胞数据集、宿主共生菌基因组与比较共线性资源。当前版本覆盖 1121 个物种,其中 152 个有核基因组、177 个有线粒体基因组、591 个有转录组数据、5 个有单细胞数据集(共 209 802 个细胞),另含 30 个细菌共生菌基因组。
来源:Nucleic Acids Research · doi.org
Annelids inhabit marine, freshwater, and terrestrial ecosystems and are important models for studying animal evolution, regeneration, and host–microbe interactions, yet their rapidly growing omics resources remain dispersed across repositories and publications. We developed AnnelidaDB (www.annelidadb.com), a species-centred database built on an updated phylogenetic framework that integrates genomes, mitochondrial genomes, transcriptomes, proteomes, epigenomes, single-cell datasets, host-associated symbiont genomes, and comparative synteny for Annelida. The current release covers 1121 species, including 152 species with nuclear genomes, 177 with mitochondrial genomes, 591 with transcriptome data, 5 with single-cell datasets comprising 209 802 cells, and 30 bacterial symbiont genomes. AnnelidaDB organizes these resources through 10 navigation directories and connects species, genome, gene, functional annotation, and gene-family records. Users can browse genomic assemblies, explore interactive single-cell atlases and 12 200 precomputed Oxford plots, run BLAST queries and search genes against the annelid-specific database, and submit chromosome-level data for syntenic analysis against 20 Annelida linkage groups. Sequences, annotations, and private results are available for download. As a comprehensive multi-omics resource dedicated to annelids, AnnelidaDB provides an accessible platform for comparative investigations of annelid genome evolution, adaptation, regeneration, and symbiosis.